Biotransformation Question bank

Q1. Which of the following statements is NOT true about Phase I biotransformation reactions? a) They introduce or expose functional groups on drugs.b) They can increase the polarity of drugs.c) They always make drugs more water-soluble. d) They prepare drugs for further metabolism in Phase II.e) Oxidation, reduction, and hydrolysis are the primary reactions. Q2. … Read more

Pharmacokinetics

Pharmacokinetics = cellular process by which ions and molecules move across the cell membrane. Cell membrane = barrier that separates the interior of the cell (cytoplasm) from the outside environment. Drug Absroption The process by which drug is absorbed in systemic circulation from the site of administration. Factors affecting drug Absroption 1. Physicochemical Properties of … Read more

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